Universal Leukoreduction of Cellular Blood Components in 2001?
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چکیده
منابع مشابه
Universal leukoreduction of cellular blood components in 2001? No.
Leukocytes are known to have a number of biologic effects associated with allogeneic blood transfusion ❚Table 1❚. The potential clinical importance of these effects, which are the focus of current debate over the merits of “universal” leukocyte reduction (leukoreduction; cellular components with <5 × 106 leukocytes) include the following: febrile-associated transfusion reactions (FATRs), transf...
متن کاملUniversal leukoreduction of cellular blood components in 2001? Yes.
During the past 100 years, transfusion medicine has focused on introducing improvements in technology to increase the safety of blood transfusion. The initial obstacle to safe transfusion was the problem of acute hemolysis. 1,2 During the first 8 decades of the 20th century, much attention was given to compatibility testing, such that, by the latter decades, incompatible transfusions became inc...
متن کاملTo filter blood or universal leukoreduction: what is the answer?
The safety of the blood supply has been a concern over the past 20-30 years because of the transmission of infectious diseases. Blood is still routinely tested for viruses, and leukoreduction is an effective strategy to reduce the transmission of cell-associated viruses. Clinically, the benefits of leukoreduction include decreases in transfusion reactions, HLA alloimmunization, infections, feve...
متن کاملIs there justification for universal leukoreduction?
The Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH), the institution that represents the Associação Médica Brasileira (AMB) in respect to hematology, transfusion therapy and cell therapy in Brazil hereby states: Prospective randomized studies have not demonstrated any positive clinical impact with the universal use of blood components in which the initial number of le...
متن کاملAge of transfused blood: an independent predictor of mortality despite universal leukoreduction.
BACKGROUND The transfusion of relatively older stored blood has been associated with an increased risk of multiple organ failure, infection, and death. It remains unknown whether this phenomenon is mitigated by transfusion of leukoreduced red cell units. The purpose of this study was to evaluate the influence of stored blood age on mortality in injured patients who universally received leukored...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2001
ISSN: 0002-9173,1943-7722
DOI: 10.1309/xg61-nb7q-jm59-pk98